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HEALTHY LIVING
Deadly Poisonous: Hidden Risks in Fish and Shellfish - P1/2  
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	Next I will talk about 
the tropical sea fish toxin. 
It is found in fish in 
the tropical, subtropical, 
and temperate zones. 
Eating these fish, even if 
caught alive, and cooked 
immediately, could 
lead to food poisoning. 
  
Welcome 
veg-embracing viewers 
to another episode of 
Healthy Living. 
Today we present part one 
in our two-part series 
on seafood poisoning 
which is caused by 
consuming fish 
or shellfish 
tainted with toxins. 
In the USA it is 
the primary cause of 
foodborne illness. 
  
Typical symptoms of 
seafood poisoning 
include nausea, vomiting, 
gastroenteritis, 
muscle aches, and in the 
most serious cases, death.
With globalization 
making it possible for 
contaminated marine life 
to be sold in markets 
worldwide, no one 
who consumes seafood
is free from 
this dangerous threat.
  
There are eight 
main types of fish and 
shellfish poisoning. 
The most well-known 
involving fish are: 
CIGUATERA 
SCOMBROID 
TETRODOTOXIN 
and MERCURY
  
The most common 
varieties of shellfish 
poisoning include: 
PARALYTIC, 
DIARRHEAL
AMNESIC  
and NEUROTOXIC    
  
CIGUATERA
POISONING
  
We start with ciguatera 
which is caused by 
ciguatoxins, a poison 
produced by algae 
called dinoflagellates, 
which are found 
across the world. 
During summer months, 
the dinoflagellates 
proliferate in coastal 
waters creating what are 
known as algal blooms.  
Their population size 
may become so great that 
the waters appear red 
in color because of 
the pigment in the algae, 
a phenomenon known as 
“red tides.” 
  
Ciguatera comes from 
microscopic algae which 
grow upon the surface 
of coral and 
other larger algae. 
And that gets consumed 
by herbivorous fish 
and it goes up 
through the food chain. 
The toxin accumulates 
within the flesh 
of the larger fish. 
That’s what people 
tend to consume and 
they become poisoned 
after eating that. 
  
Ciguatera, 
the most common type of 
fish poisoning worldwide, 
may be contracted from 
eating tropical reef fish, 
such as grouper, 
snapper, sea bass, 
and parrotfish
as well as farmed salmon. 
Each year an estimated 
50,000 cases 
occur globally. 
A total of 400 marine 
species are known to 
bioaccumulate ciguatoxins, 
which are 1,000 times 
more lethal than arsenic. 
  
The illness is marked by 
such symptoms as severe 
gastrointestinal distress, 
nausea, abnormally low 
heart rate, convulsions, 
and blurred vision 
to name just a few. 
Relapses can occur 
by consuming seafood, 
chicken, pork, coffee 
or alcohol and may 
happen for years after 
eating the tainted fish.
  
Ciguatoxins are resistant 
to heat and cold, 
so cooking, smoking, 
refrigerating, freezing 
and/or curing 
the poisoned fish cannot 
protect a consumer from 
becoming sickened. 
It is also undetectable 
as the toxin is 
odorless and tasteless.
  
When a person eats 
a ciguateric fish and 
gets ciguatera, 
the symptoms come on 
after about one  to six, 
even up to 24 hours and 
then you can get up to 
30 or even more different 
symptoms from this 
one poisoning event. 
  
And these range from 
your common food 
poisoning symptoms like 
vomiting and diarrhea, 
as well as nausea and 
gut pains to non-specific 
effects; you get fatigue, 
you get muscle aches, 
joint aches and then
 a wide range of 
neurological symptoms 
including bizarre 
temperature reversal that 
causes pain on contact 
with cold objects, 
but also you get 
numbness and tingling 
in the extremities. 
  
You get a whole range of 
things like itching that 
jumps around the body.
Ciguatera is one of 
the worst food poisonings, 
because the symptoms 
last for weeks, months 
and sometimes even years. 
So this very long, 
protracted illness makes 
people wonder, and often 
they don’t even 
get diagnosed properly.
  
SCOMBROID 
POISONING
  
Scombroid, the second 
most widespread type 
of fish poisoning 
after ciguatera, is 
the result of ingesting 
decayed fish, with 
symptoms sometimes 
appearing within minutes 
of consuming the flesh. 
Fish that may carry 
scombroid include 
Sardine, Anchovy, 
Herring, and Amberjack.
  
Among all the marine 
toxin poisoning, 
the most common one 
in Formosa (Taiwan) 
is scombrotoxin 
fish poisoning, also 
known as histamine fish 
poisoning, resulting 
from consuming 
dark meat fish, such as
Mackerel, Marlin, 
Bonito, and Tuna. 
This kind of fish contains 
histidine, so if they are 
not properly stored, 
the bacteria will turn 
histidine into histamine. 
  
When it’s combined with 
other amines such as 
putrescin, or cadaverine, 
it will cause symptoms 
similar to 
histamine poisoning, 
including rash, fever, 
dizziness, headache, 
upset stomach, vomiting 
and hives. 
Such cases have 
happened every year 
in Formosa (Taiwan) 
in the past few years. 
  
Some other possible 
consequences of 
scombroid poisoning 
include 
burning sensations 
around the mouth, 
facial flushing, and 
abnormal heartbeat. 
Cooking or freezing 
a fish will not 
neutralize the toxin.
  
TETRODOTOXIN 
POISONING
  
Pufferfish naturally 
have tetrodotoxin in 
their bodies and 
poisoning may occur 
after one eats “Fugu” or 
a Japanese dish 
made of Pufferfish. 
Tetrodotoxin is one 
of nature’s most fatal 
poisons and is 10,000 
times more potent 
than cyanide. 
If an adult consumes 
just 0.001 milligram 
of the substance, 
the outcome could be 
deadly. 
  
The mortality rate for 
tetrodotoxin-sickened 
individuals is estimated 
to be up to 50%, and 
no antidote is known 
to exist. 
Cooking or freezing 
the fish does not remove 
its toxic properties and 
the amount of poison 
in just one Pufferfish 
could kill 30 adults.
Besides Pufferfish, 
Ocean Sunfish, 
Triggerfish, and 
Porcupine Fish 
contain tetrodotoxin. 
These species can be 
found in tropical and 
semi-tropical waters 
across the globe. 
  
Cases of 
Pufferfish poisoning 
have also been found
in Formosa (Taiwan) 
and occasionally in other 
countries in the world. 
It’s not very common, but 
it happens occasionally. 
The Pufferfish is 
actually very toxic. 
It has a kind of 
neurotoxin element. 
  
Pufferfish poisoning 
happens when people 
catch Pufferfish 
and eat it.
The symptoms caused 
by Pufferfish poisoning 
include numbness in the 
mouth and in the tongue. 
In the more serious cases, 
the numbness might 
extend to the limbs and 
cause respiratory failure 
and death. 
  
Tetrodotoxin can kill. 
At the moment, there’s no 
real way of treating them 
apart from some form of 
first aid, or trying to 
get the toxin out of 
the person’s stomach 
so no more of it 
can get taken up. 
Some cases 
you can consume 
activated charcoal which 
can be used to try and 
absorb the toxin and 
prevent it being taken up 
through your stomach 
and the rest of your gut. 
But if you get 
a significant dose of 
those toxins it is fatal. 
  
The tetrodotoxin blocks 
a protein in our nerves 
called the sodium channel. 
This is a protein 
that allows sodium ions 
to go across the nerve 
membrane and that is 
how we create biological 
electricity in our bodies. 
So of course if you close 
that sodium channel and 
prevent your biological 
electricity from working, 
basically your nervous 
system and other tissues 
like your muscles 
just literally shut down. 
And so because of that, 
you’ll die. 
  
Tetrodotoxin is 
not just found in fish. 
Some gastropods, 
a type of mollusk, also 
produce this poison.
  
Regarding
the tiny gastropods 
smaller than a thumb, 
not only is their meat 
poisonous, 
but also their intestines. 
Lots of poisoning cases 
have occurred in 
Formosa (Taiwan), 
such as in Pingtung. 
Eating more than ten 
of these tiny gastropods 
could cost you your life. 
It also happened 
in Dongshan Island. 
Depending on 
the intensity of the toxin, 
sometimes eating two 
is enough to be fatal. 
You see, the gastropods 
are only that big, yet two 
of them can get you killed.
  
MERCURY 
POISONING
  
Methylmercury is 
a neurotoxin and 
is the most lethal form 
of mercury, an element 
which occurs naturally, 
but can also enter 
the environment though 
industrial emissions 
from sources like 
coal-burning plants.  
A joint Harvard University, 
USA and US Geological 
Survey study published 
in 2009 concluded that 
mercury-laden emissions 
from industrial activity 
get into the oceans, 
are changed into 
methylmercury 
by bacteria and then 
bioaccumulate in 
different ocean species. 
  
A mother who consumes 
mercury-contaminated 
fish or other seafood puts 
their fetus at high risk 
of birth defects including 
mental retardation, 
cerebral palsy, blindness 
and deafness. 
In adults, mercury 
poisoning from seafood 
can cause memory loss, 
tremors, vision loss, 
heart disease, and death. 
Like other toxins, 
mercury is undetectable 
in fish as it is 
odorless and tasteless.
  
PARALYTIC 
SHELLFISH 
POISONING
  
Saxitoxin causes paralytic 
shellfish poisoning 
and is produced 
by dinoflagellates.  
The toxins in these algae 
become accumulated 
in the bodies of 
filter feeders like clams, 
oysters, and scallops. 
Saxitoxin-tainted 
shellfish are found 
globally, but most often 
in temperate waters. 
  
There is another kind of 
marine toxin poisoning, 
paralytic shellfish 
poisoning, which 
is not common 
but has happened 
in many countries. 
We know from its name 
that it’s resulted from 
eating shellfish, such as 
Coelomactra antiquate. 
The toxin of shellfish 
is about the same 
as tetrodotoxin. 
After eating it, it will 
poison our nervous system. 
It can also cause 
numbness in the mouth, 
the tongue and the limbs.
  
In the most serious 
poisoning cases, 
muscle paralysis and 
respiratory failure may 
occur followed by death 
within two to 25 hours.
  
NEUROTOXIC
SHELLFISH 
POISONING
  
Brevetoxins are 
responsible for 
neurotoxic 
shellfish poisoning 
and come from 
dinoflagellates. 
Consuming contaminated 
oysters, clams, or mussels 
can lead to 
gastrointestinal upset, 
tingling in the mouth, 
arms and legs, 
incoordination, and even 
temperature reversal 
like with ciguatera.
  
AMNESIC 
SHELLFISH 
POISONING
  
The toxin associated 
with amnesic shellfish 
poisoning is from a type 
of red-brown algae that is 
found in the oceans 
surrounding Europe, 
North America, East Asia 
and Southeast Asia. 
The less severe effects 
of poisoning include 
dizziness, headache, 
and disorientation, 
but amnesia and death 
may also occur.
  
Other toxins are things 
like domoic acid, which 
is the cause of amnesic 
shellfish poisoning, 
which is 
a rare occurrence. 
But as you can tell from 
the name what it does is 
it affects the human brain 
and people actually 
forget about 
what’s happened.
  
DIARRHEAL 
SHELLFISH 
POISONING
  
Another syndrome is 
something called 
diarrhetic shellfish 
poisoning. 
Obviously again 
from the name, it causes 
very bad diarrhea and 
that’s caused by a toxin 
called okadaic acid. 
And again, that comes 
from a microscopic algae 
that can form these 
blooms that people see 
as part of red tides. 
  
It has a very difficult to 
treat diarrhea problem 
in that it causes 
the epithelium 
of people’s gut linings 
to actually slough off, 
so it’s not like something 
you can rush down 
to the chemist and 
get an anti-diarrhetic 
to try and deal with it. 
It’s quite a severe form 
of diarrhea.  
  
As we have seen today, 
the risks associated with 
consuming fish and 
shellfish are extremely 
high and the possible 
devastating results 
include death. 
Doctors Lyndon Llewellyn, 
Hwang Deng-Fwu and 
Yang Chen-Chang, and 
Professor Richard Lewis, 
we thank you 
for taking time from 
your busy schedules to 
discuss the issue of 
seafood poisoning 
and the toxins 
hidden in marine life. 
May humankind soon 
stop eating all animal 
products and instead 
adopt the safe, nutritious 
and delicious 
organic vegan diet.
  
For more details on 
the experts featured 
on today’s program, 
please visit 
the following websites 
Dr. Lyndon Llewellyn
AIMS.gov.au 
Professor Richard Lewis
www.IMB.UQ.edu.au 
Dr. Hwang Deng-Fwu
www.Toxin.NTOU.edu.tw 
Dr. Yang Chen-Chang
www.VGHTPE.gov.tw
  
Treasured viewers, 
please join us again 
next Monday 
on Healthy Living for 
part two of our program 
on the hazards of 
eating fish and shellfish. 
Coming up next is 
Science and Spirituality 
after Noteworthy News. 
May Heaven bless you 
with everlasting 
vitality and well-being.       
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